#StructuralBiology has historically been an #OpenScience.
The Protein Databank was established in 1971, and you could write to them requesting the 7 structures available at the time be mailed to you (presumably on tape).
https://www.rcsb.org/pages/about-us/history
Now the PDB contains over 225,000 experimentally determined structures. Most structural biology software (Phenix, CCP4, Relion, CCPEM, CCPN) is open source.
Deepmind published AF3 in Nature but did not release the code (as per Nature requirements).