xtaldave.net is one of the many independent Mastodon servers you can use to participate in the fediverse.
Currently a Mastodon server for Xtaldave, a London-based Structural Biologist.

Server stats:

1
active users

#molecularbiology

3 posts3 participants0 posts today

Four years after publishing my work on machine-driven parameter screen of biochemical reactions, it still has zero citations. That makes me sad; I am really proud of this work. So I asked ChatGPT to suggest me hashtags, for another chance to reach readers. academic.oup.com/nar/article/4 #MolecularBiology #BiochemicalReactions #ReverseTranscription #RNASequencing #LabAutomation #GeneExpression #SingleCellAnalysis #HighThroughput #AIinScience #ComputationalBiology #BiotechInnovation #DataDrivenResearch

25 years after the Human Genome Project draft, we're in a "post-genomic" age.

This era explores key biological questions, blending genomics with environmental and social factors to address health disparities.

undark.org/2024/12/05/opinion-

Undark Magazine · What Does It Mean to Be In the 'Post-Genomic' Age?Opinion | New dialogues are emerging about what comes next in biology, 25 years after completion of a draft of the human genome.

📚 Our latest paper "Dimerization of ADAR1 modulates site-specificity of RNA editing" is finally out at Nature Communications 🧑‍🔬👩‍🔬 Structural insights led to an engineered mutant, offering a molecular tool for targeting dimerization. 🎯 Read more about the fascinating interplay between ADAR1 dimerization and RNA editing in our study conducted with M. Jantsch Lab (MedUni Vienna): nature.com/articles/s41467-024 🧬#RNAEditing #ADAR1 #MolecularBiology

If you want to read how small non-coding satellite RNA (#satRNA) molecules affect #virus transmission by insects, (and the mitigating/accelerating effect of satRNA on this process) - please read our preprint on plant viruses: PSV, CMV and their satRNAs

biorxiv.org/content/10.1101/20
#plantscience #biology #molecularbiology, #virology #science

bioRxiv · Symptom-modulating satRNAs of cucumoviruses affect the orientation and feeding behaviour of Myzus persicaePlant viruses evolved mechanisms to manipulate host plants to replicate and be efficiently transmitted by insect vectors. In the context of non-persistently transmitted viruses, an important strategy is to change the plant’s metabolism to attract the vectors, and subsequently repel viruliferous insects from the infected plants to facilitate the virus transmission to neighbouring plants. The presence of satellite RNAs (satRNAs), which accompany certain plant RNA virus species and strains, leads to changes in the host plants, such as alterations in the virus-induced infection symptoms, either exacerbating or attenuating them. This study aimed to analyse the influence of satRNAs on the orientation and feeding behaviour of the cucumovirus insect vector – Myzus persicae , which might consequently contribute to the virus transmission efficiency. The hypothesis behind this study was that satRNAs of cucumoviruses alter these insect activities toward virus-infected plants, and strongly symptom-deteriorating satRNAs might negatively affect the attractiveness of the infected plants for aphids. Using two cucumoviruses, peanut stunt virus (PSV) and cucumber mosaic virus (CMV), and their satRNAs, which induce divergent infection symptoms, olfactometry and electrical penetration graph (EPG) monitoring analyses were performed. The results showed that satRNAs which presence leads to disease symptom exacerbation might alter the orientation behaviour of aphids by reducing the attractiveness of the plants and discouraging aphids from feeding. This phenomenon may contribute to the better persistence in the environment of satRNAs alleviating disease symptoms compared to the worsening ones, benefiting the virus by not destroying the plant and prolonging the virus’ exposure to insect vectors. ### Competing Interest Statement The authors have declared no competing interest.

If you want to read how small non-coding satellite RNA (#satRNA) molecules affect #virus transmission by insects, (and the mitigating/accelerating effect of satRNA on this process) - please read our preprint on plant viruses: PSV, CMV and their satRNAs

biorxiv.org/content/10.1101/20
#plantscience #biology #molecularbiology, #virology #science

bioRxiv · Symptom-modulating satRNAs of cucumoviruses affect the orientation and feeding behaviour of Myzus persicaePlant viruses evolved mechanisms to manipulate host plants to replicate and be efficiently transmitted by insect vectors. In the context of non-persistently transmitted viruses, an important strategy is to change the plant’s metabolism to attract the vectors, and subsequently repel viruliferous insects from the infected plants to facilitate the virus transmission to neighbouring plants. The presence of satellite RNAs (satRNAs), which accompany certain plant RNA virus species and strains, leads to changes in the host plants, such as alterations in the virus-induced infection symptoms, either exacerbating or attenuating them. This study aimed to analyse the influence of satRNAs on the orientation and feeding behaviour of the cucumovirus insect vector – Myzus persicae , which might consequently contribute to the virus transmission efficiency. The hypothesis behind this study was that satRNAs of cucumoviruses alter these insect activities toward virus-infected plants, and strongly symptom-deteriorating satRNAs might negatively affect the attractiveness of the infected plants for aphids. Using two cucumoviruses, peanut stunt virus (PSV) and cucumber mosaic virus (CMV), and their satRNAs, which induce divergent infection symptoms, olfactometry and electrical penetration graph (EPG) monitoring analyses were performed. The results showed that satRNAs which presence leads to disease symptom exacerbation might alter the orientation behaviour of aphids by reducing the attractiveness of the plants and discouraging aphids from feeding. This phenomenon may contribute to the better persistence in the environment of satRNAs alleviating disease symptoms compared to the worsening ones, benefiting the virus by not destroying the plant and prolonging the virus’ exposure to insect vectors. ### Competing Interest Statement The authors have declared no competing interest.

#introduction on a new instance.

Dad and husband in #Pennsylvania. Teach #biochemistry, #molecularbiology, and #microbiology (and #humanities) in #highered.

Using #Emacs daily since the late 80s, #GNU #Linux on and off since the 90s. Moved to strictly #FreeSoftware five years ago or so. #Debian, #GrapheneOS, #OrgMode, #OBS and #Emacs for teaching and research.

#Japanese #日本語, #francais, y #espanol roto. #DnD and #bookclub with my cronies. Love #camping #hiking #walking #cycling #coding.